Giuliana Silvestri is Clinical Reader and Consultant Ophthalmic Surgeon at the Belfast Health & Social Care Trust. Dr Silvestri’s clinical interests are in diseases of the retina such as diabetes, age-related macular degeneration, inflammatory ocular disease and inherited retinal dystrophies. Her programme of research has focused on genetic predisposition and causative genetic mutations in ophthalmic diseases with emphasis on age-related macular degeneration and inherited retinal disorders. Her group has gathered well-characterized patient DNA repositories and contributed to local and international genotyping programmes and has developed collaborations with leading groups in the USA. The groups’ work on genetic predisposition in AMD has contributed to the scienfic background for a commercial assay for genetic risk testing in AMD.This work on AMD predisposition is clinically relevant as early predictive testing may allow preventative strategies thereby limiting visual loss. Dr Silvestri Is Lead of the Northern Ireland Clinical Research Group for Vision which continuous to grow and has a portfolio of commercial studies. Dr Silvestri has just finished longstanding terms as Training Programme Director for Northern Ireland and as Head of Student Support for the Medical School. She hopes that her recent appointment as Clinical Director for Ophthalmic Services at the Belfast Health& Social Care Trust will allow her to reshape services and further integrate clinical and laboratory research.